Mechanical Ventilation Guided by Electrical Impedance Tomography in Children With Acute Lung Injury.

ABSTRACT:

Objectives

To provide proof-of-concept for a protocol applying a strategy of personalized mechanical ventilation in children with acute respiratory distress syndrome. Positive end-expiratory pressure and inspiratory pressure settings were optimized using real-time electrical impedance tomography aiming to maximize lung recruitment while minimizing lung overdistension.

Design

Prospective interventional trial.

Setting

Two PICUs.

Patients

Eight children with early acute respiratory distress syndrome (< 72 hr).

Interventions

On 3 consecutive days, electrical impedance tomography-guided positive end-expiratory pressure titration was performed by using regional compliance analysis. The Acute Respiratory Distress Network high/low positive end-expiratory pressur

SUBMITTER: Rosemeier I 

PROVIDER: S-EPMC7063910 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature