Ontology highlight
ABSTRACT:
SUBMITTER: Mehrabi P
PROVIDER: S-EPMC7064102 | biostudies-literature | 2020 Mar
REPOSITORIES: biostudies-literature
Mehrabi Pedram P Müller-Werkmeister Henrike M HM Leimkohl Jan Philipp JP Schikora Hendrik H Ninkovic Jelena J Krivokuca Silvia S Andriček Ladislav L Epp Sascha W SW Sherrell Darren D Owen Robin L RL Pearson Arwen R AR Tellkamp Friedjof F Schulz Eike C EC Miller R J Dwayne RJD
Journal of synchrotron radiation 20200227 Pt 2
Serial synchrotron crystallography (SSX) is an emerging technique for static and time-resolved protein structure determination. Using specifically patterned silicon chips for sample delivery, the `hit-and-return' (HARE) protocol allows for efficient time-resolved data collection. The specific pattern of the crystal wells in the HARE chip provides direct access to many discrete time points. HARE chips allow for optical excitation as well as on-chip mixing for reaction initiation, making a large n ...[more]