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Chikungunya fever outbreak identified in North Bali, Indonesia.


ABSTRACT: Background:Chikungunya virus (CHIKV) infections have been reported sporadically within the last 5 years in several areas of Indonesia including Bali. Most of the reports, however, have lacked laboratory confirmation. Method:A recent fever outbreak in a village in the North Bali area was investigated using extensive viral diagnostic testing including both molecular and serological approaches. Results and conclusions:Ten out of 15 acute febrile illness samples were confirmed to have CHIKV infection by real-time PCR or CHIKV-specific IgM enzyme-linked immunosorbent assay (ELISA). The outbreak strain belonged to the Asian genotype with highest homology to other CHIKV strains currently circulating in Indonesia. The results are of public health concern particularly because Bali is a popular tourist destination in Indonesia and thereby the potential to spread the virus to non-endemic areas is high. GenBank accession numbers:KY885022, KY885023, KY885024, KY885025, KY885026, KY885027.

SUBMITTER: Sari K 

PROVIDER: S-EPMC7064274 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature

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Chikungunya fever outbreak identified in North Bali, Indonesia.

Sari Kartika K   Myint Khin Saw Aye KSA   Andayani Ayu Rai AR   Adi Putu Dwi PD   Dhenni Rama R   Perkasa Aditya A   Ma'roef Chairin Nisa CN   Witari Ni Putu Diah NPD   Megawati Dewi D   Powers Ann M AM   Jaya Ungke Anton UA  

Transactions of the Royal Society of Tropical Medicine and Hygiene 20170701 7


<h4>Background</h4>Chikungunya virus (CHIKV) infections have been reported sporadically within the last 5 years in several areas of Indonesia including Bali. Most of the reports, however, have lacked laboratory confirmation.<h4>Method</h4>A recent fever outbreak in a village in the North Bali area was investigated using extensive viral diagnostic testing including both molecular and serological approaches.<h4>Results and conclusions</h4>Ten out of 15 acute febrile illness samples were confirmed  ...[more]

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