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Assessing left ventricular systolic function in children with a history of Kawasaki disease.


ABSTRACT: BACKGROUND:The incidence of Kawasaki disease (KD) is increasing. Indeed, KD has become the most common cause of acquired heart disease in children. Previous studies have well summarized the acute phase left ventricular (LV) systolic dysfunction using speckle tracking echocardiography (STE); however, changes in LV systolic function after long-term follow-up remain unclear. METHODS:One hundred children with a history of KD, but without coronary artery aneurysms, were enrolled. These children were divided into two subgroups based on the presence or absence of coronary artery dilatation (CAD). The duration of follow-up was >?7?years. The control group consisted of 51 healthy children. The LV myocardial strain were measured by two- and three-dimensional STE. RESULTS:Two-dimensional STE not only revealed that LV longitudinal strain decreased in part of segments in both KD groups, but also showed that global strain decreased in the KD group with CAD compared to the controls (P?

SUBMITTER: Lin Z 

PROVIDER: S-EPMC7068877 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature

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Assessing left ventricular systolic function in children with a history of Kawasaki disease.

Lin Zhou Z   Zheng Jingjing J   Chen Weiling W   Ding Tingting T   Yu Wei W   Xia Bei B  

BMC cardiovascular disorders 20200312 1


<h4>Background</h4>The incidence of Kawasaki disease (KD) is increasing. Indeed, KD has become the most common cause of acquired heart disease in children. Previous studies have well summarized the acute phase left ventricular (LV) systolic dysfunction using speckle tracking echocardiography (STE); however, changes in LV systolic function after long-term follow-up remain unclear.<h4>Methods</h4>One hundred children with a history of KD, but without coronary artery aneurysms, were enrolled. These  ...[more]

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