Ontology highlight
ABSTRACT:
SUBMITTER: Grassi A
PROVIDER: S-EPMC7068963 | biostudies-literature | 2020 Mar
REPOSITORIES: biostudies-literature
Grassi Alice A Ferlicca Daniela D Lupieri Ermes E Calcinati Serena S Francesconi Silvia S Sala Vittoria V Ormas Valentina V Chiodaroli Elena E Abbruzzese Chiara C Curto Francesco F Sanna Andrea A Zambon Massimo M Fumagalli Roberto R Foti Giuseppe G Bellani Giacomo G
Critical care (London, England) 20200312 1
<h4>Background</h4>Diaphragm atrophy and dysfunction are consequences of mechanical ventilation and are determinants of clinical outcomes. We hypothesize that partial preservation of diaphragm function, such as during assisted modes of ventilation, will restore diaphragm thickness. We also aim to correlate the changes in diaphragm thickness and function to outcomes and clinical factors.<h4>Methods</h4>This is a prospective, multicentre, observational study. Patients mechanically ventilated for m ...[more]