Dataset Information

Bedtimes and Blood Pressure: A Prospective Cohort Study of Mexican Adolescents.

ABSTRACT:

Introduction

Hypertension affects up to 5% of children worldwide and predicts later cardiovascular morbidity. Associations of short sleep and hypertension have been frequently reported in adults but less consistently in children. This study aims to examine the role of late bedtimes, a marker of short sleep duration, and potentially misaligned circadian rhythms, on incident elevated blood pressure (BP) in a large cohort of Mexican children.

Methods

Participants included 2,033 adolescents recruited from public schools in Morelos, Mexico, free from elevated BP (<90th sex, age, and height-standardized percentile). Fourteen months later, all adolescents had a second BP assessment. We abstracted baseline habitual bedtimes from questionnaires to evaluate the association between bedtime and elevated BP incidence (?90th percentile). Risk ratios and 95% confidence intervals were estimated with discrete-time mixed survival models, adjusting for potential confounders and accounting for clustering by school.

Results

Participants were 12.5 (SD?=?0.6) years old at baseline. At the follow-up visit 10% of adolescents had developed elevated BP. Compared to participants with a habitual weekday bedtime between 9 and 10 pm, those with a weekday bedtime 11 pm or later had a 1.87 times higher risk of developing elevated BP over the follow-up period (95% CI = 1.09, 2.21), after accounting for confounders. Participants with earlier weekday bedtimes also had a higher risk of elevated BP (RR?=?1.96; 95% CI = 1.27, 3.01). The associations persisted after accounting for wake time.

Conclusion

These data showed a U-shaped association between weekday bedtime and elevated/high BP risk among Mexican adolescents.

SUBMITTER: Jansen EC

PROVIDER: S-EPMC7069344 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature

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Publications

Bedtimes and Blood Pressure: A Prospective Cohort Study of Mexican Adolescents.

Jansen Erica C EC Dunietz Galit Levi GL Matos-Moreno Amilcar A Solano Maritsa M Lazcano-Ponce Eduardo E Sánchez-Zamorano Luisa María LM

American journal of hypertension 20200301 3

<h4>Introduction</h4>Hypertension affects up to 5% of children worldwide and predicts later cardiovascular morbidity. Associations of short sleep and hypertension have been frequently reported in adults but less consistently in children. This study aims to examine the role of late bedtimes, a marker of short sleep duration, and potentially misaligned circadian rhythms, on incident elevated blood pressure (BP) in a large cohort of Mexican children.<h4>Methods</h4>Participants included 2,033 adole ...[more]

PMID: 31840156

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Dataset Information

Bedtimes and Blood Pressure: A Prospective Cohort Study of Mexican Adolescents.

Introduction

Methods

Results

Conclusion

Publications

Bedtimes and Blood Pressure: A Prospective Cohort Study of Mexican Adolescents.

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