Ontology highlight
ABSTRACT:
SUBMITTER: Winanto
PROVIDER: S-EPMC7069952 | biostudies-literature | 2020 Mar
REPOSITORIES: biostudies-literature
Cell death & disease 20200313 3
Mutations in mitochondrial DNA (mtDNA), typically maternally inherited, can result in severe neurological conditions. There is currently no cure for mitochondrial DNA diseases and treatments focus on management of the symptoms rather than correcting the defects downstream of the mtDNA mutation. Mitochondrial encephalomyopathy, lactic acidosis and stroke-like episodes (MELAS) is one such mitochondrial disease that affects many bodily systems, particularly the central nervous system and skeletal m ...[more]