Ontology highlight
ABSTRACT:
SUBMITTER: Zhang C
PROVIDER: S-EPMC7070056 | biostudies-literature | 2020 Mar
REPOSITORIES: biostudies-literature
Zhang Changping C Liu Zixuan Z Zhang Yuhao Y Ma Liang L Song Erqun E Song Yang Y
Cell death & disease 20200313 3
Exposure to nanomaterials (NMs) is an emerging threat to human health, and the understanding of their intracellular behavior and related toxic effects is urgently needed. Ferroptosis is a newly discovered, iron-mediated cell death that is distinctive from apoptosis or other cell-death pathways. No evidence currently exists for the effect of "iron free" engineered NMs on ferroptosis. We showed by several approaches that (1) zinc oxide nanoparticles (ZnO NPs)-induced cell death involves ferroptosi ...[more]