Ontology highlight
ABSTRACT:
SUBMITTER: Li J
PROVIDER: S-EPMC7070090 | biostudies-literature | 2020 Mar
REPOSITORIES: biostudies-literature
Communications biology 20200313 1
Directed differentiation methods allow acquisition of high-purity cardiomyocytes differentiated from human induced pluripotent stem cells (hiPSCs); however, their immaturity characteristic limits their application for drug screening and regenerative therapy. The rapid electrical pacing of cardiomyocytes has been used for efficiently promoting the maturation of cardiomyocytes, here we describe a simple device in modified culture plate on which hiPSC-derived cardiomyocytes can form three-dimension ...[more]