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I Am a Compassionate Conservation Welfare Scientist: Considering the Theoretical and Practical Differences Between Compassionate Conservation and Conservation Welfare.

ABSTRACT: Compassionate Conservation and Conservation Welfare are two disciplines whose practitioners advocate consideration of individual wild animals within conservation practice and policy. However, they are not, as is sometimes suggested, the same. Compassionate Conservation and Conservation Welfare are based on different underpinning ethics, which sometimes leads to conflicting views about the kinds of conservation activities and decisions that are acceptable. Key differences between the disciplines appear to relate to their views about which wild animals can experience harms, the kinds of harms they can experience and how we can know about and confidently evidence those harms. Conservation Welfare scientists seek to engage with conservation scientists with the aim of facilitating ongoing incremental improvements in all aspects of conservation, i.e., minimizing harms to animals. In contrast, it is currently unclear how the tenets of Compassionate Conservation can be used to guide decision-making in complex or novel situations. Thus, Conservation Welfare may offer modern conservationists a more palatable approach to integrating evidence-based consideration of individual sentient animals into conservation practice and policy.

SUBMITTER: Beausoleil NJ

PROVIDER: S-EPMC7070475 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature

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I Am a Compassionate Conservation Welfare Scientist: Considering the Theoretical and Practical Differences Between Compassionate Conservation and Conservation Welfare.

Beausoleil Ngaio J NJ

Animals : an open access journal from MDPI 20200206 2

Compassionate Conservation and Conservation Welfare are two disciplines whose practitioners advocate consideration of individual wild animals within conservation practice and policy. However, they are not, as is sometimes suggested, the same. Compassionate Conservation and Conservation Welfare are based on different underpinning ethics, which sometimes leads to conflicting views about the kinds of conservation activities and decisions that are acceptable. Key differences between the disciplines ...[more]

PMID: 32041150

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Project description:IntroductionWork and family trajectories develop and interact over the life course in complex ways. Previous studies drew a fragmented picture of these trajectories and had limited scope. We provide the most comprehensive study of early-to-midlife work-family trajectories to date.MethodsUsing retrospective data from waves 3 and 7 of the Survey of Health, Aging and Retirement in Europe (SHARE), we reconstructed work-family trajectories from age 15 to 49 among almost 80,000 individuals born between 1908 and 1967 across 28 countries. We applied multichannel sequence and cluster analysis to identify typical trajectories and multinomial logistic regression models to uncover their social composition.ResultsThe results revealed six common trajectories. The dominant and therefore standard trajectory represents continuous full-time employment with having a partner and children. Women, the lower educated and persons from conservative and liberal welfare regimes are underrepresented in this trajectory, whereas men, higher educated people and those from social-democratic, Eastern European and Baltic welfare regimes are overrepresented. The other trajectories denote a deviation from the standard one, integrating a non-standard form of work with standard family formation or vice versa. Mothers in a stable relationship generally work part-time or not at all. When mostly in full-time employment, women are more likely to be divorced. Lower educated persons are less likely to have work-family trajectories characterized by full-time work and a non-standard family, yet more likely to be non-employed for large parts of their life with standard family formation. Younger cohorts are underrepresented in non-employment trajectories, but overrepresented in part-time employment trajectories along with a partner and children as well as full-time employment trajectories with divorce. Individuals from Southern European and liberal regimes are more likely to be non-working and self-employed partnered parents and those from social-democratic regimes are more likely to be full-time employed divorced parents. We also found pronounced gender differences in how educational level, birth cohort and welfare regime are associated with work-family trajectories from early to midlife.DiscussionOur findings highlight the socially stratified nature of earlier-life work-family trajectories in Europe. Potential implications for inequalities in later life are discussed.

Project description:During a 1-year compassionate use program, 156 patients with migraine self-administered a monthly dose of erenumab 140 mg with a subcutaneous autoinjector. Main inclusion criteria were: ≥ 4 migraine days/month and ≥two prior prophylactic treatment failures. The patients covered the migraine severity spectrum from episodic migraine (EM) (n = 80) to chronic migraine (CM) (n = 76). During the 3rd month of treatment, monthly headache days decreased by 45.7% in EM and 35.5% in CM. The 50% responder rate for reduction in monthly headache days was significantly higher in EM (55%) than in CM (43%) (p = 0.05). In both the migraine subgroups, the clinical improvement vs. baseline was already significant during the 1st month of treatment (p < 0.001). There were also significant reductions in mean headache severity, duration, and monthly days with acute drug intake. The 30% responder rate at 3 months was 60% in CM and 54.1% of patients reversed from CM to EM. The therapeutic effect was maintained at 12 months when 50% responder rates, considering discontinuation for lack of efficacy or adverse effects as 0% response, still were 51% in EM and 41% in CM. A total of 10 patients with EM (12.5%) and 23 patients with CM (30.3%) had discontinued treatment, considering the treatment as ineffective. At 3 months, 48% of patients reported non-serious adverse events among which the most frequent was constipation (20.5%); corresponding figures at 12 months were 30 and 15%. Discontinuation due to an adverse effect for the entire 12 month period was rare (3.8%). The lower efficacy in CM than in EM was mainly due to a very low 50% responder rate in patients with CM with continuous pain (13%) as compared to CM with pain-free periods (58%) (p < 0.001). Similarly, the 50% responder rate was lower in patients with ≥two prior prophylactic treatment failures (40.5%) compared to those with two failures (70%) (p < 0.05). There was no significant efficacy difference between low (4-7 migraine days/month, n = 22) and high frequency (8-14 days, n = 59) EM nor between patients with CM with (n = 50) or without (n = 26) acute medication overuse. Erenumab had no effect on the frequency of auras. Taken together, erenumab 140 mg monthly was highly effective for migraine prophylaxis over the whole severity spectrum of the disease, except in patients with continuous headaches. Its effect is significant after the first injection, quasi-maximal after the second injection, and does not wear off after 12 months. The most frequent adverse effect was constipation. These results are compared to those published for erenumab in the pivotal randomized placebo-controlled trials and to those reported in several recent real-world studies.

Dataset Information

I Am a Compassionate Conservation Welfare Scientist: Considering the Theoretical and Practical Differences Between Compassionate Conservation and Conservation Welfare.

Publications

I Am a Compassionate Conservation Welfare Scientist: Considering the Theoretical and Practical Differences Between Compassionate Conservation and Conservation Welfare.

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