Knockout Mouse Models for Peroxiredoxins.
Ontology highlight
ABSTRACT:
SUBMITTER: Lee YJ
PROVIDER: S-EPMC7070531 | biostudies-literature | 2020 Feb
REPOSITORIES: biostudies-literature
Publications
Knockout Mouse Models for Peroxiredoxins.
Antioxidants (Basel, Switzerland) 20200222 2
Peroxiredoxins (PRDXs) are members of a highly conserved peroxidase family and maintain intracellular reactive oxygen species (ROS) homeostasis. The family members are expressed in most organisms and involved in various biological processes, such as cellular protection against ROS, inflammation, carcinogenesis, atherosclerosis, heart diseases, and metabolism. In mammals, six PRDX members have been identified and are subdivided into three subfamilies: typical 2-Cys (PRDX1, PRDX2, PRDX3, and PRDX4 ...[more]
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