Ontology highlight
ABSTRACT:
SUBMITTER: Wang CY
PROVIDER: S-EPMC7070788 | biostudies-literature | 2020 Mar
REPOSITORIES: biostudies-literature
Wang Ching-Yu CY Pham Phuong N PN Kim Sarah S Lingineni Karthik K Schmidt Stephan S Diaby Vakaramoko V Brown Joshua J
Clinical and translational science 20200213 2
Generic entry of newer anticoagulants is expected to decrease the costs of atrial fibrillation management. However, when making switches between brand and generic medications, bioequivalence concerns are possible. The objectives of this study were to predict and compare the lifetime cost-effectiveness of brand dabigatran with hypothetical future generics. Markov microsimulations were modified to predict the lifetime costs and quality-adjusted life years of patients on either brand or generic dab ...[more]