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Anticancer Potential of Resveratrol, ?-Lapachone and Their Analogues.


ABSTRACT: This review aims to explore the potential of resveratrol, a polyphenol stilbene, and beta-lapachone, a naphthoquinone, as well as their derivatives, in the development of new drug candidates for cancer. A brief history of these compounds is reviewed along with their potential effects and mechanisms of action and the most recent attempts to improve their bioavailability and potency against different types of cancer.

SUBMITTER: Ferraz da Costa DC 

PROVIDER: S-EPMC7070981 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature

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Anticancer Potential of Resveratrol, β-Lapachone and Their Analogues.

Ferraz da Costa Danielly C DC   Pereira Rangel Luciana L   Martins-Dinis Mafalda Maria Duarte da Cunha MMDDC   Ferretti Giulia Diniz da Silva GDDS   Ferreira Vitor F VF   Silva Jerson L JL  

Molecules (Basel, Switzerland) 20200218 4


This review aims to explore the potential of resveratrol, a polyphenol stilbene, and beta-lapachone, a naphthoquinone, as well as their derivatives, in the development of new drug candidates for cancer. A brief history of these compounds is reviewed along with their potential effects and mechanisms of action and the most recent attempts to improve their bioavailability and potency against different types of cancer. ...[more]

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