Ontology highlight
ABSTRACT:
SUBMITTER: Mandelli GE
PROVIDER: S-EPMC7072276 | biostudies-literature | 2020 Jan
REPOSITORIES: biostudies-literature
Mandelli Giulio Eugenio GE Missale Francesco F Bresciani Debora D Gatta Luisa Benerini LB Scapini Patrizia P Caveggion Elena E Roca Elisa E Bugatti Mattia M Monti Matilde M Cristinelli Luca L Belotti Sandra S Simeone Claudio C Calza Stefano S Melocchi Laura L Vermi William W
Cells 20200125 2
<h4>Background</h4>Urothelial bladder cancers (UBCs) are distinct in two main molecular subtypes, namely basal and luminal type. Subtypes are also diverse in term of immune contexture, providing a rationale for patient selection to immunotherapy.<h4>Methods</h4>By digital microscopy analysis of a muscle-invasive BC (MIBC) cohort, we explored the density and clinical significance of CD66b<sup>+</sup> tumor-associated-neutrophils (TAN) and CD3<sup>+</sup> T cells. Bioinformatics analysis of UBC da ...[more]