Ontology highlight
ABSTRACT:
SUBMITTER: Singh AK
PROVIDER: S-EPMC7072504 | biostudies-literature | 2020 Jan
REPOSITORIES: biostudies-literature
Singh Anand-Krishna AK Patel Pankaj Kumar PK Choudhary Komal K Joshi Jaya J Yadav Dhananjay D Jin Jun-O JO
Biomolecules 20200131 2
Quercetin and coumarin, two naturally occurring phytochemicals of plant origin, are known to regulate hyperglycemia and oxidative stress. The present study was designed to evaluate the inhibitory activity of quercetin and coumarin on dipeptidyl peptidase-IV (DPP-IV) and their antioxidant potential. DPP-IV inhibition assays were performed, and evaluated IC<sub>50</sub> values of diprotin A, quercetin, coumarin, and sitagliptin were found to be 0.653, 4.02, 54.83, and 5.49 nmol/mL, respectively. F ...[more]