Ontology highlight
ABSTRACT:
SUBMITTER: Lamb LS
PROVIDER: S-EPMC7072681 | biostudies-literature | 2020 Jan
REPOSITORIES: biostudies-literature
Lamb Lydia S LS Sim Hao-Wen HW McCormack Ann I AI
Cancers 20200128 2
Aggressive pituitary tumors account for up to 10% of pituitary tumors and are characterized by resistance to medical treatment and multiple recurrences despite standard therapies, including surgery, radiotherapy, and chemotherapy. They are associated with increased morbidity and mortality, particularly pituitary carcinomas, which have mortality rates of up to 66% at 1 year after diagnosis. Novel targeted therapies under investigation include mammalian target of rapamycin (mTOR), tyrosine kinase, ...[more]