NK Cell-Based Immunotherapy in Renal Cell Carcinoma.
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ABSTRACT:
SUBMITTER: Terren I
PROVIDER: S-EPMC7072691 | biostudies-literature | 2020 Jan
REPOSITORIES: biostudies-literature
Publications
NK Cell-Based Immunotherapy in Renal Cell Carcinoma.
Terrén Iñigo I Orrantia Ane A Mikelez-Alonso Idoia I Vitallé Joana J Zenarruzabeitia Olatz O Borrego Francisco F
Cancers 20200129 2
Natural killer (NK) cells are cytotoxic lymphocytes that are able to kill tumor cells without prior sensitization. It has been shown that NK cells play a pivotal role in a variety of cancers, highlighting their relevance in tumor immunosurveillance. NK cell infiltration has been reported in renal cell carcinoma (RCC), the most frequent kidney cancer in adults, and their presence has been associated with patients' survival. However, the role of NK cells in this disease is not yet fully understood ...[more]
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