Ontology highlight
ABSTRACT:
SUBMITTER: Rotundo F
PROVIDER: S-EPMC7072756 | biostudies-literature | 2020 Feb
REPOSITORIES: biostudies-literature
Rotundo Federica F Cominetti Denis D El Bezawy Rihan R Percio Stefano S Doldi Valentina V Tortoreto Monica M Zuco Valentina V Valdagni Riccardo R Zaffaroni Nadia N Gandellini Paolo P
Cells 20200213 2
The development of novel therapies or the improvement of currently used approaches to treat prostate cancer (PCa), the most frequently diagnosed male tumor in developed countries, is an urgent need. In this regard, the functional characterization of microRNAs, molecules shown to regulate a number of cancer-related pathways, is instrumental to their possible clinical exploitation. Here, we demonstrate the tumor-suppressive role of the so far uncharacterized <i>miR-1272</i>, which we found to be s ...[more]