Ontology highlight
ABSTRACT:
SUBMITTER: Figlioli G
PROVIDER: S-EPMC7073216 | biostudies-literature | 2020 Jan
REPOSITORIES: biostudies-literature
Cancers 20200126 2
Germline protein truncating variants (PTVs) in the <i>FANCM</i> gene have been associated with a 2-4-fold increased breast cancer risk in case-control studies conducted in different European populations. However, the distribution and the frequency of <i>FANCM</i> PTVs in Europe have never been investigated. In the present study, we collected the data of 114 European female breast cancer cases with <i>FANCM</i> PTVs ascertained in 20 centers from 13 European countries. We identified 27 different ...[more]