Background Diet Influences TMAO Concentrations Associated with Red Meat Intake without Influencing Apparent Hepatic TMAO-Related Activity in a Porcine Model.
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ABSTRACT:
SUBMITTER: Thogersen R
PROVIDER: S-EPMC7074160 | biostudies-literature | 2020 Feb
REPOSITORIES: biostudies-literature
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Background Diet Influences TMAO Concentrations Associated with Red Meat Intake without Influencing Apparent Hepatic TMAO-Related Activity in a Porcine Model.
Thøgersen Rebekka R Rasmussen Martin Krøyer MK Sundekilde Ulrik K UK Goethals Sophie A SA Van Hecke Thomas T Vossen Els E De Smet Stefaan S Bertram Hanne Christine HC
Metabolites 20200206 2
Red meat has been associated with an increased cardiovascular disease (CVD) risk, possibly through gut microbial-derived trimethylamine-N-oxide (TMAO). However, previous reports are conflicting, and influences from the background diet may modulate the impact of meat consumption. This study investigated the effect of red and white meat intake combined with two different background diets on urinary TMAO concentration and its association with the colon microbiome in addition to apparent hepatic TMA ...[more]
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