Ontology highlight
ABSTRACT:
SUBMITTER: Pinter E
PROVIDER: S-EPMC7074469 | biostudies-literature | 2020 Feb
REPOSITORIES: biostudies-literature
Pinter Elisabeth E Rainer Bernhard B Czerny Thomas T Riegel Elisabeth E Schilter Benoît B Marin-Kuan Maricel M Tacker Manfred M
Foods (Basel, Switzerland) 20200222 2
<h4>Background</h4>Non-targeted screening of food contact materials (FCM) for non-intentionally added substances (NIAS) reveals a great number of unknown and unidentified substances present at low concentrations. In the absence of toxicological data, the application of the threshold of toxicological concern (TTC) or of EU Regulation 10/2011 requires methods able to fulfill safety threshold criteria. In this review, mammalian <i>in vitro</i> genotoxicity assays are analyzed for their ability to d ...[more]