Ontology highlight
ABSTRACT:
SUBMITTER: Rego A
PROVIDER: S-EPMC7074882 | biostudies-literature | 2020 Feb
REPOSITORIES: biostudies-literature
Rego Adriana A Sousa António G G AGG Santos João P JP Pascoal Francisco F Canário João J Leão Pedro N PN Magalhães Catarina C
Microorganisms 20200218 2
Bacterial natural products (NPs) are still a major source of new drug leads. Polyketides (PKs) and non-ribosomal peptides (NRP) are two pharmaceutically important families of NPs and recent studies have revealed Antarctica to harbor endemic polyketide synthase (PKS) and non-ribosomal peptide synthetase (NRPS) genes, likely to be involved in the production of novel metabolites. Despite this, the diversity of secondary metabolites genes in Antarctica is still poorly explored. In this study, a comp ...[more]