Ontology highlight
ABSTRACT:
SUBMITTER: Chen B
PROVIDER: S-EPMC7075166 | biostudies-literature | 2020 Feb
REPOSITORIES: biostudies-literature
Nanomaterials (Basel, Switzerland) 20200202 2
ZnO NPs have been assessed to show adverse effects on reproductive organs, but the molecular mechanisms of reproductive toxicity have not been sufficiently studied. In this research, the dosage effects from the oral exposure of ZnO NPs (30 nm) to pregnant mice in gestation day 10.5 to 17.5 was analyzed. Pregnant mice exposed to ZnO NPs induced dam injury, mice fetal growth restriction, and the fetus number decreased. The pathological evaluation showed that ZnO NPs exposure caused placental spong ...[more]