Ontology highlight
ABSTRACT:
SUBMITTER: Hanna RD
PROVIDER: S-EPMC7075644 | biostudies-literature | 2016 Oct
REPOSITORIES: biostudies-literature
Journal of the American Chemical Society 20160930 40
α-Boryl ethers, carbonates, and acetals, readily prepared from the corresponding alcohols that are accessed through ketone diboration, react rapidly with hydrogen peroxide to release alcohols, aldehydes, and ketones through the collapse of hemiacetal intermediates. Experiments with α-boryl acetals containing a latent fluorophore clearly demonstrate that cargo can be released inside cells in the presence of exogenous or endogenous hydrogen peroxide. These experiments show that this protocol can b ...[more]