Ontology highlight
ABSTRACT:
SUBMITTER: Roex G
PROVIDER: S-EPMC7076393 | biostudies-literature | 2020 Feb
REPOSITORIES: biostudies-literature
Roex Gils G Feys Tom T Beguin Yves Y Kerre Tessa T Poiré Xavier X Lewalle Philippe P Vandenberghe Peter P Bron Dominique D Anguille Sébastien S
Pharmaceutics 20200224 2
Chimeric antigen receptor (CAR)-T-cell therapy is an innovative form of adoptive cell therapy that has revolutionized the treatment of certain hematological malignancies, including B-cell non-Hodgkin lymphoma (NHL) and B-cell acute lymphoblastic leukemia (ALL). The treatment is currently also being studied in other B-cell neoplasms, including multiple myeloma (MM) and chronic lymphocytic leukemia (CLL). CD19 and B-cell maturation antigen (BCMA) have been the most popular target antigens for CAR- ...[more]