Ontology highlight
ABSTRACT:
SUBMITTER: Zhang J
PROVIDER: S-EPMC7077056 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Zhang Jizhou J Gao Yue Y Wang Peng P Zhi Hui H Zhang Yan Y Guo Maoni M Yue Ming M Li Xin X Zhou Dianshuang D Wang Yanxia Y Shen Weitao W Wang Junwei J Huang Jian J Ning Shangwei S
Frontiers in bioengineering and biotechnology 20200310
Identification and characterization of lncRNAs in cancer with a view to their application in improving diagnosis and therapy remains a major challenge that requires new and innovative approaches. We have developed an integrative framework termed "CLING", aimed to prioritize candidate cancer-related lncRNAs based on their associations with known cancer lncRNAs. CLING focuses on joint optimization and prioritization of all candidates for each cancer type by integrating lncRNA topological propertie ...[more]