Ontology highlight
ABSTRACT:
SUBMITTER: Pickar-Oliver A
PROVIDER: S-EPMC7079207 | biostudies-literature | 2019 Aug
REPOSITORIES: biostudies-literature
Pickar-Oliver Adrian A Gersbach Charles A CA
Nature reviews. Molecular cell biology 20190801 8
The prokaryote-derived CRISPR-Cas genome editing systems have transformed our ability to manipulate, detect, image and annotate specific DNA and RNA sequences in living cells of diverse species. The ease of use and robustness of this technology have revolutionized genome editing for research ranging from fundamental science to translational medicine. Initial successes have inspired efforts to discover new systems for targeting and manipulating nucleic acids, including those from Cas9, Cas12, Cas ...[more]