The role of lipocalin-2 in age-related macular degeneration (AMD).
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ABSTRACT:
SUBMITTER: Ghosh S
PROVIDER: S-EPMC7079812 | biostudies-literature | 2020 Mar
REPOSITORIES: biostudies-literature
Publications
The role of lipocalin-2 in age-related macular degeneration (AMD).
Ghosh Sayan S Stepicheva Nadezda N Yazdankhah Meysam M Shang Peng P Watson Alan M AM Hose Stacey S Liu Haitao H Weiss Joseph J Zigler J Samuel JS Valapala Mallika M Watkins Simon C SC Sinha Debasish D
Cellular and molecular life sciences : CMLS 20200104 5
Lipocalins are a family of secreted adipokines which play important roles in various biological processes. Lipocalin-2 (LCN-2) has been shown to be involved in acute and chronic inflammation. This particular protein is critical in the pathogenesis of several diseases including cancer, diabetes, obesity, and multiple sclerosis. Herein, we discuss the general molecular basis for the involvement of LCN-2 in acute infections and chronic disease progression and also ascertain the probable role of LCN ...[more]
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