Ontology highlight
ABSTRACT:
SUBMITTER: Wytock TP
PROVIDER: S-EPMC7080498 | biostudies-literature | 2020 Mar
REPOSITORIES: biostudies-literature
Science advances 20200318 12
The relationship between microscopic observations and macroscopic behavior is a fundamental open question in biophysical systems. Here, we develop a unified approach that-in contrast with existing methods-predicts cell type from macromolecular data even when accounting for the scale of human tissue diversity and limitations in the available data. We achieve these benefits by applying a <i>k</i>-nearest-neighbors algorithm after projecting our data onto the eigenvectors of the correlation matrix ...[more]