Ontology highlight
ABSTRACT:
SUBMITTER: Huang S
PROVIDER: S-EPMC7080656 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Frontiers in cell and developmental biology 20200312
The increasing risk of long-term adverse effects from radiotherapy on the cardiovascular structure is receiving increasing attention. However, the mechanisms underlying this increased risk remain poorly understood. Recently, the nucleotide-binding domain and leucine-rich-repeat-containing family pyrin 3 (NLRP3) inflammasome was suggested to play a critical role in radiation-induced cardiovascular injury. However, the relationship between ionizing radiation and the NLRP3 inflammasome in acute and ...[more]