Structural and functional brain abnormalities in children with schizotypal disorder: a pilot study.
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ABSTRACT:
SUBMITTER: Wang Y
PROVIDER: S-EPMC7080771 | biostudies-literature | 2020 Mar
REPOSITORIES: biostudies-literature
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Structural and functional brain abnormalities in children with schizotypal disorder: a pilot study.
Wang Ya Y Harding Ian H IH Testa Renee R Tonge Bruce B Jones Harvey H Seal Marc M Ross Nola N Chan Raymond C K RCK van Beurden Florian F Abu-Akel Ahmad A Skafidas Efstratios E Pantelis Christos C
NPJ schizophrenia 20200318 1
Schizotypal disorder lies in the schizophrenia spectrum and is widely studied in adult populations. Schizotypal disorder in children (SDc) is less well described. This study examined brain morphological and functional connectivity abnormalities in SDc (12 SDc and 9 typically developing children), focusing on the default mode and executive control brain networks. Results indicated that SDc is associated with reduced grey matter volume (GMV) in superior and medial frontal gyri, and increased resti ...[more]
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