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Independent risk factors for death in patients admitted for asthma exacerbation in Taiwan.


ABSTRACT: The independent risk factors for death in patients admitted for asthma exacerbation have not been thoroughly investigated. This study aimed to investigate these independent risk factors and the relationship between mortality and the prescription patterns of anti-asthmatic medications in patients admitted for asthma exacerbation. Using a nested case-control design, we identified 267 cases (death after asthma admission) and 1035 controls (survival after asthma admission) from the Taiwan National Health Insurance Research Database (NHIRD) from 2001 to 2010. Conditional logistic regressions were used to estimate the odds ratios (ORs) with 95% confidence intervals (CIs). We identified the independent risk factors for death as the comorbidities of pneumonia (aOR 3.82, 95% CI 2.41-6.05), genitourinary disease (aOR 1.75, 95% CI 1.17-2.62), septicemia (aOR 4.26, 95% CI 2.61-6.94), diabetes mellitus (aOR 2.10, 95% CI 1.30-3.38), arrhythmia (aOR 2.00, 95% CI 1.14-3.50), and a history of asthmatic hospitalization (aOR 4.48, 95% CI 2.77-7.25). Moreover, the use of short-acting ?2-agonist (SABA) and the dosage of oral corticosteroids (OCSs) >70?mg prednisolone during previous hospitalization (all p?

SUBMITTER: Chang YL 

PROVIDER: S-EPMC7081219 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature

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Independent risk factors for death in patients admitted for asthma exacerbation in Taiwan.

Chang Yuh-Lih YL   Ko Hsin-Kuo HK   Lu Meng-Shui MS   Chou Chia-Lin CL   Su Kang-Cheng KC   Hsu Chia-Chen CC   Chou Kun-Ta KT   Chen Tzeng-Ji TJ   Perng Diahn-Warng DW   Chou Yueh-Ching YC  

NPJ primary care respiratory medicine 20200319 1


The independent risk factors for death in patients admitted for asthma exacerbation have not been thoroughly investigated. This study aimed to investigate these independent risk factors and the relationship between mortality and the prescription patterns of anti-asthmatic medications in patients admitted for asthma exacerbation. Using a nested case-control design, we identified 267 cases (death after asthma admission) and 1035 controls (survival after asthma admission) from the Taiwan National H  ...[more]

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