Collagen type VI ?5 gene variations may predict the risk of lung cancer development in Chinese Han population.
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ABSTRACT:
SUBMITTER: Duan Y
PROVIDER: S-EPMC7081318 | biostudies-literature | 2020 Mar
REPOSITORIES: biostudies-literature
Publications
Collagen type VI α5 gene variations may predict the risk of lung cancer development in Chinese Han population.
Duan Ying Y Liu Gaowen G Sun Yao Y Wu Jiamin J Xiong Zichao Z Jin Tianbo T Chen Mingwei M
Scientific reports 20200319 1
The abundant expression of collagen type VI α5 (COL6A5) exists in lung tissue, and its role in lung cancer is still unknown. We performed a genetic association study with an attempt to detect the relationships between single nucleotide polymorphisms (SNPs) in COL6A5 and lung cancer predisposition in Chinese Han population. We finally selected six tag-SNPs to determine their genotypes among 510 lung cancer patients and 495 healthy controls with the MassARRAY platform. The associations of SNPs and ...[more]
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