Ontology highlight
ABSTRACT:
SUBMITTER: Wade B
PROVIDER: S-EPMC7081491 | biostudies-literature | 2020 Mar
REPOSITORIES: biostudies-literature
Wade Ben B Keyburn Anthony L AL Haring Volker V Ford Mark M Rood Julian I JI Moore Robert J RJ
Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc 20200110 2
Two putative zinc metalloproteases encoded by <i>Clostridium perfringens</i> have been implicated in the pathogenesis of necrotic enteritis, an economically significant poultry disease that is caused by this anaerobic bacterium. These proteases have ~64% amino acid identity and are encoded by the <i>zmpA</i> and <i>zmpB</i> genes. We screened 83 <i>C. perfringens</i> isolates by PCR for the presence of these genes. The first gene, <i>zmpB</i>, is chromosomally located and was present in all scre ...[more]