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The median effective dose (ED50) of cis-Atracurium for laryngeal mask airway insertion during general Anaesthesia for patients undergoing urinary surgery.


ABSTRACT: BACKGROUND:In clinical practice, the laryngeal mask airway is an easy-to-use supraglottic airway device. However, the cis-atracurium dosage for laryngeal mask insertion has not been standardised. We aimed to determine the optimal dose of cis-atracurium using a sequential method for successful laryngeal mask insertion. METHODS:The cohort study protocol is registered at clinicaltrial.gov (NCT-03668262). Twenty-three patients undergoing elective urinary surgery were sequentially administered cis-atracurium doses as follows: 150, 100, 70, 50, 30, and 20??g·kg-?1. The main outcome involved the determination of the response to laryngeal mask airway insertion: ?16 points and?

SUBMITTER: Wang X 

PROVIDER: S-EPMC7081559 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature

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The median effective dose (ED50) of cis-Atracurium for laryngeal mask airway insertion during general Anaesthesia for patients undergoing urinary surgery.

Wang Xiaohua X   Huang Ke K   Yan Hao H   Lan Fei F   Yao Dongxu D   Li Yanhong Y   Xue Jixiu J   Wang Tianlong T  

BMC anesthesiology 20200319 1


<h4>Background</h4>In clinical practice, the laryngeal mask airway is an easy-to-use supraglottic airway device. However, the cis-atracurium dosage for laryngeal mask insertion has not been standardised. We aimed to determine the optimal dose of cis-atracurium using a sequential method for successful laryngeal mask insertion.<h4>Methods</h4>The cohort study protocol is registered at clinicaltrial.gov (NCT-03668262). Twenty-three patients undergoing elective urinary surgery were sequentially admi  ...[more]

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