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Effectiveness of exercise on fatigue in hemodialysis patients: a randomized controlled trial.

ABSTRACT: Background:Hemodialysis is one of the common therapies in patients with end-stage renal disease. Even patients who receive regular treatment suffer from fatigue, which is one of the main factors leading to poor quality of life. This study aimed to determine the effectiveness of exercising on mini-bikes on fatigue in hemodialysis patients. Methods:This study is a randomized controlled clinical trial. Thirty-seven hemodialysis patients participated in the study. The patients were randomly allocated to either the intervention group (n?=?20) or the control group (n?=?17). The participants in the intervention group exercised on mini-bikes for 20?min twice a week for 3 months. The patients' fatigue was measured four times during and after the intervention. Multidimensional Fatigue Inventory was used to measure the fatigue level. The total score in the MFI is 4 to 20 for each domain, with the resulting total fatigue score ranging from 20 to 100; thus, the higher the score, the higher the level of fatigue. Data were analyzed by SPSS 18. The repeated measures ANOVA was used to compare the fatigue scores within each group and between the groups at different times. Results:The mean score of fatigue in the intervention group at the beginning was 58.80?±?15.29, which steadily decreased to 58.78?±?13.54, 58.75?±?14.73, 54.20?±?15.16, and 54.23?±?13.60 for the 3?months of intervention and 1 month post-intervention, respectively. In contrast, in the control group, this score was 62.53?±?16.32 in the beginning, increasing to 64.03?±?13.91, 64.22?±?13.07, 69.53?±?9.22, for the 3?months of intervention and 70.34?±?7.69 one-month post-intervention. There were significant differences between the intervention group and the control group in the third month (P?=?0.001) and 1 month after the intervention (P?

SUBMITTER: Salehi F

PROVIDER: S-EPMC7081561 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature

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Effectiveness of exercise on fatigue in hemodialysis patients: a randomized controlled trial.

Salehi Farzaneh F Dehghan Mahlagha M Mangolian Shahrbabaki Parvin P Ebadzadeh Mohammad Reza MR

BMC sports science, medicine & rehabilitation 20200318

<h4>Background</h4>Hemodialysis is one of the common therapies in patients with end-stage renal disease. Even patients who receive regular treatment suffer from fatigue, which is one of the main factors leading to poor quality of life. This study aimed to determine the effectiveness of exercising on mini-bikes on fatigue in hemodialysis patients.<h4>Methods</h4>This study is a randomized controlled clinical trial. Thirty-seven hemodialysis patients participated in the study. The patients were ra ...[more]

PMID: 32206314

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Project description:BackgroundFibromyalgia (FM) affects approximately 1-3 % of the general population. Fatigue limits the work ability and social life of patients with FM. A few studies of physical exercise have included measures of fatigue in FM, indicating that exercise can decrease fatigue levels. There is limited knowledge about the effects of resistance exercise on multiple dimensions of fatigue in FM. The present study is a sub-study of a multicenter randomized controlled trial in women with FM. The purpose of the present sub-study was to examine the effects of a person-centered progressive resistance exercise program on multiple dimensions of fatigue in women with FM, and to investigate predictors of the potential change in fatigue.MethodsA total of 130 women with FM (age 22-64 years) were included in this assessor-blinded randomized controlled multicenter trial examining the effects of person-centered progressive resistance exercise compared with an active control group. The intervention was performed twice a week for 15 weeks. Outcomes were five dimensions of fatigue measured with the Multidimensional Fatigue Inventory (MFI-20). Information about background was collected and the women also completed several health-related questionnaires. Multiple linear stepwise regression was used to analyze predictors of change in fatigue in the total population.ResultsA higher improvement was found at the post-treatment examination for change in the resistance exercise group, as compared to change in the active control group in the MFI-20 subscale of physical fatigue (resistance group Δ -1.7, SD 4.3, controls Δ 0.0, SD 2.7, p = 0.013), with an effect size of 0.33. Sleep efficiency was the strongest predictor of change in the MFI-20 subscale general fatigue (beta = -0.54, p = 0.031, R (2) = 0.05). Participating in resistance exercise (beta = 1.90, p = 0.010) and working fewer hours per week (beta = 0.84, p = 0.005) were independent significant predictors of change in physical fatigue (R (2) = 0.14).ConclusionsPerson-centered progressive resistance exercise improved physical fatigue in women with FM when compared to an active control group.Trial registrationClinicalTrials.gov NCT01226784 . Registered 21 October 2010.

Project description:BACKGROUND:There is strong evidence that physical exercise in the workplace is effective for reducing workers' musculoskeletal complaints. Studies with industrial workers and studies on progressive resistance exercises during breaks are scarce. Our aim was to evaluate the effects of a resistance exercise program on perceived fatigue control among industrial workers. METHODS:204 employees from the dairy industry were allocated to two groups, the intervention group (IG) (n?=?98) and the control group (CG) (n?=?106). The primary outcome measures were perceived fatigue control and maximum muscle strength, measured through the Need for Recovery Scale and one-repetition maximum contraction (1-RM), respectively. Secondary outcome measures were musculoskeletal complaints, physical activity level, perceived risk factors, physical fitness (BMI, vital signs, and body fat percentage), and workers´ productivity. All outcomes were assessed at baseline and then again after 4 months. The IG performed resistance exercises using progressively greater loads while the CG performed general exercise using elastic bands. The exercise protocols were performed three times per week for 20 min. An intention-to-treat analysis was performed using the mixed linear model. Results were considered significant when p?<?0.05. RESULTS:The IG did not show to be superior to the CG, although both groups improved perceived fatigue control and muscle strength after the resistance physical exercise program in the worplace. There was also no significant difference between the groups for musculoskeletal complaints and other secondary variables analyzed. However, both groups showed significant improvements between baseline and after 4 months of intervention for all evaluated outcomes (p?<?0.05). CONCLUSION:The implementation of a progressive resistance exercise program during work breaks for perceived fatigue control was no more effective than exercises using elastic bands. However, resistance exercises during work breaks presented better results on all measured outcomes regardless of the exercise protocol used. TRIAL REGISTRATION:U.S. National Institutes of Health, ClinicalTrials.gov Identifier: NCT02172053. Registered 19 June 2014.

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Effectiveness of exercise on fatigue in hemodialysis patients: a randomized controlled trial.

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Effectiveness of exercise on fatigue in hemodialysis patients: a randomized controlled trial.

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