Ontology highlight
ABSTRACT:
SUBMITTER: Bahr I
PROVIDER: S-EPMC7082404 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Bähr Ina I Spielmann Julia J Quandt Dagmar D Kielstein Heike H
Frontiers in immunology 20200313
Obesity is accompanied by a systemic chronic low-grade inflammation as well as dysfunctions of several innate and adaptive immune cells. Recent findings emphasize an impaired functionality and phenotype of natural killer (NK) cells under obese conditions. This review provides a detailed overview on research related to overweight and obesity with a particular focus on NK cells. We discuss obesity-associated alterations in subsets, distribution, phenotype, cytotoxicity, cytokine secretion, and sig ...[more]