ARHGEF38 as a novel biomarker to predict aggressive prostate cancer.
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ABSTRACT:
SUBMITTER: Liu K
PROVIDER: S-EPMC7083745 | biostudies-literature | 2020 Jun
REPOSITORIES: biostudies-literature
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ARHGEF38 as a novel biomarker to predict aggressive prostate cancer.
Liu Kun K Wang Aixiang A Ran Longke L Zhang Wanfeng W Jing Song S Wang Yujing Y Zhang Xianqin X Liu Geli G Sen Wang W Song Fangzhou F
Genes & diseases 20190403 2
Prostate cancer (PCa) metastasis is considered the leading cause of cancer death in males. Therapeutic strategies and diagnosis for stage-specific PCa have not been well understood. Rho guanine nucleotide exchange factor 38 (ARHGEF38) is related to tumor cell polarization and is frequently expressed in PCa. Microarray data of PCa were downloaded from GEO and TCGA databases. A total of 243 DEGs were screened, of which, 32 genes were upregulated. The results of enrichment analysis showed the parti ...[more]
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