Ontology highlight
ABSTRACT:
SUBMITTER: Drozdzik M
PROVIDER: S-EPMC7084425 | biostudies-literature | 2020 Feb
REPOSITORIES: biostudies-literature
Droździk Marek M Szeląg-Pieniek Sylwia S Grzegółkowska Justyna J Łapczuk-Romańska Joanna J Post Mariola M Domagała Pawel P Miętkiewski Janusz J Oswald Stefan S Kurzawski Mateusz M
International journal of molecular sciences 20200226 5
Membrane monocarboxylate transporter 1 (<i>SLC16A1</i>/MCT1) plays an important role in hepatocyte homeostasis, as well as drug handling. However, there is no available information about the impact of liver pathology on the transporter levels and function. The study was aimed to quantify <i>SLC16A1</i> mRNA (qRT-PCR) and MCT1 protein abundance (liquid chromatography-tandem mass spectrometry (LC---MS/MS)) in the livers of patients diagnosed, according to the standard clinical criteria, with hepat ...[more]