Ontology highlight
ABSTRACT:
SUBMITTER: Luo XB
PROVIDER: S-EPMC7085372 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Luo Xiao-Bo XB Xi Jian-Cheng JC Liu Zhen Z Long Yu Y Li Li-Tao LT Luo Zhan-Peng ZP Liu Dao-Hong DH
Mediators of inflammation 20200309
Rheumatoid arthritis (RA) is a worldwide chronic autoimmune inflammatory disease which is affecting approximately 1% of the total population. It is characterized by abnormal proliferation of fibroblast-like synoviocytes (FLS) and increased production of proinflammatory cytokines. In the current study, we were aiming to investigate the role of ubiquitin-specific protease 5 (USP5) in the inflammatory process in RA-FLS. Expression of USP5 was found upregulated in RA-FLS compared with that in osteoa ...[more]