Ontology highlight
ABSTRACT:
SUBMITTER: Mulbauer GD
PROVIDER: S-EPMC7086065 | biostudies-literature | 2019 Mar
REPOSITORIES: biostudies-literature
Mulbauer Greta D GD Matthew Howard W T HWT
Discoveries (Craiova, Romania) 20190331 1
Skeletal muscle tissue has inherent capacity for regeneration in response to minor injuries. However, in the case of severe trauma, tumor ablations, or in congenital muscle defects, these myopathies can cause irreversible loss of muscle mass and function, a condition referred to as volumetric muscle loss (VML). The natural muscle repair mechanisms are overwhelmed, prompting the search for new muscle regenerative strategies, such as using biomaterials that can provide regenerative signals to eith ...[more]