Ontology highlight
ABSTRACT:
SUBMITTER: Zhang YW
PROVIDER: S-EPMC7086639 | biostudies-literature | 2016 Feb
REPOSITORIES: biostudies-literature
Archives of virology 20151114 2
Mammalian orthoreoviruses (MRVs) are widespread and infect virtually all mammals. We report here the first case of a natural mutant and reassortant serotype 3 reovirus from mink in China, known as MRV3 SD-14. Whole-genome sequence analysis showed that the MRV3 SD-14 may have resulted from a reassortment involving MRVs that infected swine, humans and mink. Interestingly, the S1 segment, which encodes the viral attachment protein σ1, which influences viral virulence and cell tropism in the host, h ...[more]