Ontology highlight
ABSTRACT:
SUBMITTER: Tian YS
PROVIDER: S-EPMC7088282 | biostudies-literature | 2013 Jan
REPOSITORIES: biostudies-literature
Tian Yu-Shi YS Verathamjamras Chris C Kawashita Norihito N Okamoto Kousuke K Yasunaga Teruo T Ikuta Kazuyoshi K Kameoka Masanori M Takagi Tatsuya T
Journal of molecular modeling 20120905 1
Cyclophilin A has attracted attention recently as a new target of anti-human immunodeficiency virus type 1 (HIV-1) drugs. However, so far no drug against HIV-1 infection exhibiting this mechanism of action has been approved. To identify new potent candidates for inhibitors, we performed in silico screening of a commercial database of more than 1,300 drug-like compounds by using receptor-based docking studies. The candidates selected from docking studies were subsequently tested using biological ...[more]