Ontology highlight
ABSTRACT:
SUBMITTER: Phillips JE
PROVIDER: S-EPMC7089577 | biostudies-literature | 2012 Feb
REPOSITORIES: biostudies-literature
Phillips J E JE Jackwood M W MW McKinley E T ET Thor S W SW Hilt D A DA Acevedol N D ND Williams S M SM Kissinger J C JC Paterson A H AH Robertson J S JS Lemke C C
Virus genes 20110910 1
Full-length genome sequencing of pathogenic and attenuated (for chickens) avian coronavirus infectious bronchitis virus (IBV) strains of the same serotype was conducted to identify genetic differences between the pathotypes. Analysis of the consensus full-length genome for three different IBV serotypes (Ark, GA98, and Mass41) showed that passage in embryonated eggs, to attenuate the viruses for chickens, resulted in 34.75-43.66% of all the amino acid changes occurring in nsp 3 within a virus typ ...[more]