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Dynamic Augmentation of Left Ventricle and Mitral Valve Function With an Implantable Soft Robotic Device.

ABSTRACT: Left ventricular failure is strongly associated with secondary mitral valve regurgitation. Implantable soft robotic devices are an emerging technology that enables augmentation of a native function of a target tissue. We demonstrate the ability of a novel soft robotic ventricular assist device to dynamically augment left ventricular contraction, provide native pulsatile flow, simultaneously reshape the mitral valve apparatus, and eliminate the associated regurgitation in an Short-term large animal model of acute left ventricular systolic dysfunction.

SUBMITTER: Saeed MY

PROVIDER: S-EPMC7091510 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature

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Dynamic Augmentation of Left Ventricle and Mitral Valve Function With an Implantable Soft Robotic Device.

Saeed Mossab Y MY Van Story David D Payne Christopher J CJ Wamala Isaac I Shin Borami B Bautista-Salinas Daniel D Zurakowski David D Del Nido Pedro J PJ Walsh Conor J CJ Vasilyev Nikolay V NV

JACC. Basic to translational science 20200226 3

Left ventricular failure is strongly associated with secondary mitral valve regurgitation. Implantable soft robotic devices are an emerging technology that enables augmentation of a native function of a target tissue. We demonstrate the ability of a novel soft robotic ventricular assist device to dynamically augment left ventricular contraction, provide native pulsatile flow, simultaneously reshape the mitral valve apparatus, and eliminate the associated regurgitation in an Short-term large anim ...[more]

PMID: 32215347

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