Engineering protein nanocages as carriers for biomedical applications.
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ABSTRACT:
SUBMITTER: Bhaskar S
PROVIDER: S-EPMC7091667 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Publications
Engineering protein nanocages as carriers for biomedical applications.
Bhaskar Sathyamoorthy S Lim Sierin S
NPG Asia materials 20170407 4
Protein nanocages have been explored as potential carriers in biomedicine. Formed by the self-assembly of protein subunits, the caged structure has three surfaces that can be engineered: the interior, the exterior and the intersubunit. Therapeutic and diagnostic molecules have been loaded in the interior of nanocages, while their external surfaces have been engineered to enhance their biocompatibility and targeting abilities. Modifications of the intersubunit interactions have been shown to modu ...[more]
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