Ontology highlight
ABSTRACT:
SUBMITTER: Vannucci B
PROVIDER: S-EPMC7092387 | biostudies-literature | 2019 Nov
REPOSITORIES: biostudies-literature
Vannucci Bianca B Santosa Katherine B KB Keane Alexandra M AM Jablonka-Shariff Albina A Lu Chuieng-Yi CY Yan Ying Y MacEwan Matthew M Snyder-Warwick Alison K AK
Muscle & nerve 20190823 5
<h4>Introduction</h4>In this study we present a reproducible technique to assess motor recovery after nerve injury via neuromuscular junction (NMJ) immunostaining and electrodiagnostic testing.<h4>Methods</h4>Wild-type mice underwent sciatic nerve transection with repair. Hindlimb muscles were collected for microscopy up to 30 weeks after injury. Immunostaining was used to assess axons (NF200), Schwann cells (S100), and motor endplates (α-bungarotoxin). Compound motor action potential (CMAP) amp ...[more]