Ontology highlight
ABSTRACT:
SUBMITTER: Sousa DN
PROVIDER: S-EPMC7092666 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Sousa Dircilei Nascimento de DN Roriz Virgílio Moreira VM Oliveira Guilherme José Pimentel Lopes de GJPL Duarte Wagner Rodrigues WR Pinto Leonardo Nogueira de Miranda Pereira LNMP Vianna Leonora Maciel de Souza LMS Carneiro Fabiana Pirani FP Ferreira Vania Maria Moraes VMM
Acta cirurgica brasileira 20200320 1
<h4>Purpose</h4>To evaluate the local effect of simvastatin (SVT) combined with deproteinized bovine bone (DBB) with hydroxyapatite/β-tricalcium phosphate biphasic ceramics (HA/TCP) and with collagen sponge (CS) on bone repair in critical size defects (CSDs) in rat calvaria.<h4>Methods</h4>Forty-two 5-mm diameter CSDs were made bilaterally in the calvaria of 18 rats. The animals were allocated according to the type of biomaterial and associations used to fill the CSD. After 8 weeks, the animals ...[more]