Relationship between mRNA stability and intron presence.
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ABSTRACT:
SUBMITTER: Wang HF
PROVIDER: S-EPMC7092898 | biostudies-literature | 2007 Mar
REPOSITORIES: biostudies-literature
Publications
Relationship between mRNA stability and intron presence.
Wang Hai-Fang HF Feng Liang L Niu Deng-Ke DK
Biochemical and biophysical research communications 20070102 1
Introns were found to enhance almost every steps of gene expression except increasing mRNA stability. By analyzing the genome-wide data of mRNA stability published by someone previously, we found that human intron-containing genes have more stable mRNAs than intronless genes, and the Arabidopsis thaliana genes with the most unstable mRNAs have fewer introns than other genes in the genome. After controlling for mRNA length, we found mRNA stability is still positively correlated with intron number ...[more]
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