Ontology highlight
ABSTRACT:
SUBMITTER: Wan S
PROVIDER: S-EPMC7093909 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Oxidative medicine and cellular longevity 20200312
<h4>Background</h4>G9a, a well-known methyltransferase, plays a vital role in biological processes. However, its role in corneal neovascularization (CoNV) remains unclear. <i>Methods. In vitro</i> and <i>in vivo</i> models were assessed in hypoxia-stimulated angiogenesis and in a mouse model of alkali burn-induced CoNV. Human umbilical vein endothelial cells (HUVECs) were cultured under hypoxic conditions and different reoxygenation times to identify the molecular mechanisms involved in this pro ...[more]